6U7K

Prefusion structure of PEDV spike

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1399	152906.9	3	UniProt (Q91AV1) Pfam (PF01600) Pfam (PF19209) Pfam (PF01601)	Porcine epidemic diarrhea virus (strain CV777) (PEDV)	S glycoprotein,E2,Peplomer protein
2	D, I, N (D, I, N)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	3	In PDB GlyTouCan (G56014GC)
3	E, F, G, H, J... (E, F, G, H, J...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	12	In PDB GlyTouCan (G42666HT)
4	AA, AB, BA, BB, CA... (A, C, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	39	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 1319 (UniProt: Q91AV1)

PDB	External Database	Details
Gly 1320	-	expression tag
Ser 1321	-	expression tag
Gly 1322	-	expression tag
Tyr 1323	-	expression tag
Ile 1324	-	expression tag
Pro 1325	-	expression tag
Glu 1326	-	expression tag
Ala 1327	-	expression tag
Pro 1328	-	expression tag
Arg 1329	-	expression tag
Asp 1330	-	expression tag
Gly 1331	-	expression tag
Gln 1332	-	expression tag
Ala 1333	-	expression tag
Tyr 1334	-	expression tag
Val 1335	-	expression tag
Arg 1336	-	expression tag
Lys 1337	-	expression tag
Asp 1338	-	expression tag
Gly 1339	-	expression tag
Glu 1340	-	expression tag
Trp 1341	-	expression tag
Val 1342	-	expression tag
Leu 1343	-	expression tag
Leu 1344	-	expression tag
Ser 1345	-	expression tag
Thr 1346	-	expression tag
Phe 1347	-	expression tag
Leu 1348	-	expression tag
Gly 1349	-	expression tag
Arg 1350	-	expression tag
Ser 1351	-	expression tag
Leu 1352	-	expression tag
Glu 1353	-	expression tag
Val 1354	-	expression tag
Leu 1355	-	expression tag
Phe 1356	-	expression tag
Gln 1357	-	expression tag
Gly 1358	-	expression tag
Pro 1359	-	expression tag
Gly 1360	-	expression tag
His 1361	-	expression tag
His 1362	-	expression tag
His 1363	-	expression tag
His 1364	-	expression tag
His 1365	-	expression tag
His 1366	-	expression tag
His 1367	-	expression tag
His 1368	-	expression tag
Ser 1369	-	expression tag
Ala 1370	-	expression tag
Trp 1371	-	expression tag
Ser 1372	-	expression tag
His 1373	-	expression tag
Pro 1374	-	expression tag
Gln 1375	-	expression tag
Phe 1376	-	expression tag
Glu 1377	-	expression tag
Lys 1378	-	expression tag
Gly 1379	-	expression tag
Gly 1380	-	expression tag
Gly 1381	-	expression tag
Ser 1382	-	expression tag
Gly 1383	-	expression tag
Gly 1384	-	expression tag
Gly 1385	-	expression tag
Gly 1386	-	expression tag
Ser 1387	-	expression tag
Gly 1388	-	expression tag
Gly 1389	-	expression tag
Ser 1390	-	expression tag
Ala 1391	-	expression tag
Trp 1392	-	expression tag
Ser 1393	-	expression tag
His 1394	-	expression tag
Pro 1395	-	expression tag
Gln 1396	-	expression tag
Phe 1397	-	expression tag
Glu 1398	-	expression tag
Lys 1399	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	458720.7
Branched	Number of molecules	15
	Total formula weight	8311.7
Non-Polymers*	Number of molecules	39
	Total formula weight	8627.1
All*	Total formula weight	475659.5

*Water molecules are not included.