6U63
Mcl-1 bound to compound 17
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 156 | 17838.2 | 4 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | E, F, G, H, I... (A, B, C, D) | 2-{[(naphthalen-2-yl)sulfonyl]amino}-5-[(2-phenylethyl)sulfanyl]benzoic acid | non-polymer | 463.6 | 6 | Chemie (Q0D) | |||
| 3 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 171 - 323 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Ser 168 | - | expression tag |
| Asn 169 | - | expression tag |
| Ala 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71352.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2781.4 | |
| All* | Total formula weight | 74134.3 |
