6U5U

Electron cryomicroscopy Structure of S. cerevisiae FAS in the KS-stalled state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fatty acid synthase subunit alpha	polymer	1887	207211.5	1	UniProt (A0A140KF01) Pfam (PF18325) Pfam (PF18314) Pfam (PF00109) Pfam (PF02801) Pfam (PF01648)	Saccharomyces cerevisiae (Baker's yeast)
2	B (G)	Fatty acid synthase subunit beta	polymer	2073	231658.9	1	UniProt (P07149) Pfam (PF13452) Pfam (PF22235) Pfam (PF01575) Pfam (PF00698) Pfam (PF17828) Pfam (PF16073) Pfam (PF08354) Pfam (PF17951)	Saccharomyces cerevisiae (Baker's yeast)
3	C, F (A, G)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
4	D (A)	4'-PHOSPHOPANTETHEINE	non-polymer		358.3	1	Chemie (PNS)
5	E (G)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	1	Chemie (FMN)

Sequence modifications

G: 1 - 2051 (UniProt: P07149)

PDB	External Database	Details
Asp 2052	-	expression tag
Tyr 2053	-	expression tag
Lys 2054	-	expression tag
Asp 2055	-	expression tag
His 2056	-	expression tag
Asp 2057	-	expression tag
Gly 2058	-	expression tag
Asp 2059	-	expression tag
Tyr 2060	-	expression tag
Lys 2061	-	expression tag
Asp 2062	-	expression tag
His 2063	-	expression tag
Asp 2064	-	expression tag
Ile 2065	-	expression tag
Asp 2066	-	expression tag
Tyr 2067	-	expression tag
Lys 2068	-	expression tag
Asp 2069	-	expression tag
Asp 2070	-	expression tag
Asp 2071	-	expression tag
Asp 2072	-	expression tag
Lys 2073	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	438870.4
Non-Polymers*	Number of molecules	4
	Total formula weight	2301.5
All*	Total formula weight	441171.9

*Water molecules are not included.