6U5L
Structure of human ULK4 in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase ULK4 | polymer | 287 | 32320.1 | 1 | UniProt (Q96C45) Pfam (PF00069) | Homo sapiens (Human) | Unc-51-like kinase 4 |
| 2 | B (A) | N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine | non-polymer | 396.4 | 1 | Chemie (3RJ) | |||
| 3 | C, D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | G (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | H (A) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A: 1 - 285 (UniProt: Q96C45)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ala 172 | Lys 172 | engineered mutation |
| Ala 173 | Lys 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32320.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 870.9 | |
| All* | Total formula weight | 33191.1 |
