6U3W

Crystal structure of yeast alpha/epsilon-COP of the COPI vesicular coat

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Coatomer subunit alpha	polymer	303	33985.3	1	UniProt (P53622) Pfam (PF06957)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Alpha-coat protein,Alpha-COP,Retrieval from endoplasmic reticulum protein 1,Secretory protein 22,Suppressor of osmo-sensitivity 1
2	B (B)	Coatomer subunit epsilon	polymer	310	35474.4	1	UniProt (P40509) Pfam (PF04733)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Epsilon-coat protein,Epsilon-COP
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	D, E (A, B)	water	water		18.0	182	Chemie (HOH)

Sequence modifications

A: 900 - 1201 (UniProt: P53622)

PDB	External Database	Details
Met 899	-	initiating methionine

B: 15 - 310 (UniProt: P40509)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Gln 12	-	expression tag
Asp 13	-	expression tag
Pro 14	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69459.7
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	69551.8

*Water molecules are not included.