6U3P
Binary complex of native hAChE with oxime reactivator LG-703
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Acetylcholinesterase | polymer | 550 | 60288.0 | 2 | UniProt (P22303) Pfam (PF00135) In PDB | Homo sapiens (Human) | AChE |
| 2 | A | (2E,2'E)-N,N'-[1,4-diazepane-1,4-diyldi(ethane-2,1-diyl)]bis[2-(hydroxyimino)acetamide] | non-polymer | 328.4 | 1 | Chemie (PQY) | |||
| 3 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 547 (UniProt: P22303)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120576.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 406.5 | |
| All* | Total formula weight | 120982.5 |
