6U3A
1.65 Angstrom crystal structure of the N97S Ca-CaM:CaV1.2 IQ domain complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Calmodulin-1 | polymer | 148 | 16694.3 | 2 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (Human) | |
| 2 | B, D (C, D) | Voltage-dependent L-type calcium channel subunit alpha-1C | polymer | 37 | 4319.0 | 2 | UniProt (Q13936) | Homo sapiens (Human) | Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Voltage-gated calcium channel subunit alpha Cav1.2 |
| 3 | E, F, G, J, K... (A, B) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 4 | H, I (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | N, O, P, Q (A, C, B, D) | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 148 (UniProt: P0DP23)
C, D: 1611 - 1644 (UniProt: Q13936)
| PDB | External Database | Details |
|---|---|---|
| Ser 97 | Asn 98 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 1608 | - | expression tag |
| Asn 1609 | - | expression tag |
| Ala 1610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42026.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 326.5 | |
| All* | Total formula weight | 42353.1 |
