6U01

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84D mutant with pyruvate bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34186.2	6	UniProt (A0A2U0QMK8) Pfam (PF00701) UniProt (by SIFTS) (Q9PPB4) In PDB	Campylobacter jejuni	HTPA synthase
2	F, A, B, C, E	1,2-ETHANEDIOL	non-polymer		62.1	11	Chemie (EDO)
3	A	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
4	F, B, C	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
5	E, B, C, D	TRIETHYLENE GLYCOL	non-polymer		150.2	4	Chemie (PGE)
6	E, B, C, D	ACETATE ION	non-polymer		59.0	6	Chemie (ACT)
7	E	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	F	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
9		water	water		18.0	987	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: A0A2U0QMK8)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asp 84	Asn 84	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	205117.5
Non-Polymers*	Number of molecules	30
	Total formula weight	2176.0
All*	Total formula weight	207293.4

*Water molecules are not included.