6TZT

Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Coatomer subunit epsilon	polymer	322	36139.7	2	UniProt (O14579) Pfam (PF04733) In PDB	Homo sapiens (Human)	Epsilon-coat protein,Epsilon-COP
2	B, D	Coatomer subunit alpha	polymer	356	39975.1	2	UniProt (P53621) Pfam (PF06957) In PDB	Homo sapiens (Human)	Alpha-coat protein,Alpha-COP,HEP-COP,HEPCOP
3		water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, C: 1 - 308 (UniProt: O14579)

PDB	External Database	Details
Met -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Gln -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag

B, D: 870 - 1224 (UniProt: P53621)

PDB	External Database	Details
Met 869	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	152229.5
All*	Total formula weight	152229.5

*Water molecules are not included.