6TYX

Structure of Ku80 von Willebrand domain S229A mutant complexed with XLF Ku Binding Motif

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	X-ray repair cross-complementing protein 5	polymer	231	26170.0	2	UniProt (A0A1L8EVE5) Pfam (PF03731) UniProt (by SIFTS) (Q6DDS9) In PDB	Xenopus laevis (African clawed frog)
2	C, D	LYS-GLY-LEU-PHE-MET	polymer	18	1918.4	2	UniProt (by SIFTS) (A0A1L8ENT6) In PDB	Xenopus laevis
3		water	water		18.0	228	Chemie (HOH)

Sequence modifications

A, B: 1 - 242 (UniProt: A0A1L8EVE5)

PDB	External Database	Details
Met -6	-	initiating methionine
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
-	Glu 171	deletion
-	Glu 172	deletion
-	Phe 173	deletion
-	Gly 174	deletion
-	Gly 175	deletion
-	Ser 176	deletion
-	Ser 177	deletion
-	Asn 178	deletion
-	Asn 179	deletion
-	Arg 180	deletion
-	Gly 181	deletion
-	Asn 182	deletion
-	Ala 183	deletion
-	Gly 184	deletion
-	Ser 185	deletion
-	Ser 186	deletion
-	Asp 187	deletion
-	Arg 188	deletion
Ser 190	Cys 190	engineered mutation
Ala 229	Ser 229	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	56176.7
All*	Total formula weight	56176.7

*Water molecules are not included.