6TYE

Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (F)	RNA polymerase sigma factor	polymer	177	19563.1	1	UniProt (A0A045IR27) Pfam (PF04542) Pfam (PF04545) UniProt (by SIFTS) (P9WGH5)	Mycobacterium tuberculosis
2	B (G)	DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*G)-3')	polymer	17	5252.4	1		Mycobacterium tuberculosis
3	C (H)	DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3')	polymer	27	8373.4	1		Mycobacterium tuberculosis
4	D (I)	RNA (5'-R(P*CP*UP*CP*GP*A)-3')	polymer	5	1546.0	1		Mycobacterium tuberculosis
5	E, F (A, B)	DNA-directed RNA polymerase subunit alpha	polymer	347	37745.3	2	UniProt (A5U8D3) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) UniProt (by SIFTS) (P9WGZ1)	Mycobacterium tuberculosis	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
6	G (C)	DNA-directed RNA polymerase subunit beta	polymer	1178	130018.8	1	UniProt (P9WGY8) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (P9WGY9)	Mycobacterium tuberculosis	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
7	H (D)	DNA-directed RNA polymerase subunit beta'	polymer	1316	146969.0	1	UniProt (A0A0E8TXU5) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) UniProt (by SIFTS) (P9WGY7)	Mycobacterium tuberculosis	RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
8	I (E)	DNA-directed RNA polymerase subunit omega	polymer	110	11851.1	1	UniProt (A0A045H2R3) Pfam (PF01192) UniProt (by SIFTS) (P9WGY5)	Mycobacterium tuberculosis	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	399064.4
All*	Total formula weight	399064.4

*Water molecules are not included.