6TXO

Crystal structure of the haemagglutinin mutant (Gln226Leu, Del228) from an H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue 3'-SLN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (B, D, F)	Hemagglutinin HA2	polymer	177	20313.4	3	UniProt (A0A0A7HR51) Pfam (PF00509)	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
2	D, E, F (A, C, E)	Hemagglutinin	polymer	324	35427.1	3	UniProt (A0A0A7HR51) Pfam (PF00509)	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
3	G (G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	H, I (H, I)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose	branched		471.4	2	In PDB GlyTouCan (G30207PZ)
5	J (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6	K, L (D, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	M (C)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
8	N (E)	N-acetyl-alpha-neuraminic acid	non-polymer		309.3	1	Chemie (SIA)
9	O, P, Q, R, S... (B, D, F, A, C...)	water	water		18.0	154	Chemie (HOH)

Sequence modifications

B, D, F: 1 - 176 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Lys 177	-	expression tag

A, C, E: 2 - 323 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Asp 0	-	expression tag
Pro 1	-	expression tag
-	Gly 230	deletion

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	167221.3
Branched	Number of molecules	3
	Total formula weight	1367.2
Non-Polymers*	Number of molecules	5
	Total formula weight	853.8
All*	Total formula weight	169442.4

*Water molecules are not included.