6TXB
Crystal structure of Mindy1 mutant (P138A) in complex with Lys48 linked di-ubiquitin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin carboxyl-terminal hydrolase MINDY-1 | polymer | 289 | 31980.1 | 1 | UniProt (Q8N5J2) Pfam (PF04424) | Homo sapiens (Human) | Deubiquitinating enzyme MINDY-1,Protein FAM63A |
| 2 | B, C, D (D, H, L) | Polyubiquitin-C | polymer | 76 | 8576.8 | 3 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (Human) | |
| 3 | E, F, G, J (A, D) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | H, I (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | K, L, M, N (A, D, H, L) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A: 110 - 384 (UniProt: Q8N5J2)
| PDB | External Database | Details |
|---|---|---|
| Gly 96 | - | expression tag |
| Pro 97 | - | expression tag |
| Leu 98 | - | expression tag |
| Gly 99 | - | expression tag |
| Ser 100 | - | expression tag |
| Pro 101 | - | expression tag |
| Glu 102 | - | expression tag |
| Phe 103 | - | expression tag |
| Pro 104 | - | expression tag |
| Gly 105 | - | expression tag |
| Arg 106 | - | expression tag |
| Leu 107 | - | expression tag |
| Glu 108 | - | expression tag |
| Met 109 | - | expression tag |
| Ala 137 | Cys 137 | engineered mutation |
| Ala 138 | Pro 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57710.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 162.9 | |
| All* | Total formula weight | 57873.5 |
