6TXB

Crystal structure of Mindy1 mutant (P138A) in complex with Lys48 linked di-ubiquitin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004843	molecular_function	cysteine-type deubiquitinase activity
A	1990380	molecular_function	K48-linked deubiquitinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue NA A 401

Chain	Residue
A	HIS351

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site_id	AC2
Number of Residues	2
Details	binding site for residue NA A 402

Chain	Residue
A	TYR296
A	HOH548

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site_id	AC3
Number of Residues	3
Details	binding site for residue NA A 403

Chain	Residue
A	GLN149
A	GLU310
A	LEU311

---

site_id	AC4
Number of Residues	1
Details	binding site for residue CL A 404

Chain	Residue
A	GLU159

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site_id	AC5
Number of Residues	1
Details	binding site for residue CL A 405

Chain	Residue
A	GLU308

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site_id	AC6
Number of Residues	2
Details	binding site for residue NA D 101

Chain	Residue
D	LYS6
A	HIS270

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Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
D	LYS27-ASP52

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"27292798","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"27292798","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	75
Details	Domain: {"description":"Ubiquitin-like 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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