6TWC
Crystal Structure of the Catalytic Domain of the Coagulation Factor XIa in Complex with Double Bridged Peptide F21
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Coagulation factor XI | polymer | 244 | 27600.3 | 1 | UniProt (P03951) Pfam (PF00089) In PDB | Homo sapiens (Human) | FXI,Plasma thromboplastin antecedent,PTA |
2 | H | Coagulation factor XI | polymer | 18 | 2159.4 | 1 | UniProt (P03951) In PDB | Homo sapiens (Human) | FXI,Plasma thromboplastin antecedent,PTA |
3 | C | Double Bridged Peptide F21 | polymer | 12 | 1428.8 | 1 | synthetic construct | ||
4 | C | ACETONE | non-polymer | 58.1 | 2 | Chemie (ACN) |
Sequence modifications
A: 16 - 245 (UniProt: P03951)
H: 357 - 369 (UniProt: P03951)
PDB | External Database | Details |
---|---|---|
Gly 113 | Asn 491 | conflict |
Gly 115 | Thr 493 | conflict |
His 246 | - | expression tag |
His 247 | - | expression tag |
His 248 | - | expression tag |
His 249 | - | expression tag |
His 250 | - | expression tag |
His 251 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 352 | - | initiating methionine |
Asp 353 | - | expression tag |
Asp 354 | - | expression tag |
Asp 355 | - | expression tag |
Asp 356 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 31188.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 116.2 | |
All* | Total formula weight | 31304.7 |