6TW9
HumRadA22F in complex with CAM833
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA repair and recombination protein RadA | polymer | 231 | 25398.9 | 1 | UniProt (O74036) Pfam (PF08423) In PDB | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | |
| 2 | A | ~{N}-[2-[(2~{S},4~{R})-2-[[(1~{S})-1-(2-chloranyl-4-methoxy-phenyl)ethyl]carbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-2-oxidanylidene-ethyl]-6-fluoranyl-quinoline-2-carboxamide | non-polymer | 529.0 | 1 | Chemie (O08) | |||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A: 108 - 349 (UniProt: O74036)
| PDB | External Database | Details |
|---|---|---|
| Met 107 | - | initiating methionine |
| Ala 168 | Val 168 | engineered mutation |
| Met 169 | Ile 169 | engineered mutation |
| Tyr 170 | Trp 170 | engineered mutation |
| Leu 182 | Ile 182 | engineered mutation |
| Asp 198 | Lys 198 | engineered mutation |
| Asn 199 | His 199 | engineered mutation |
| Val 200 | Ile 200 | engineered mutation |
| Ala 201 | Tyr 201 | engineered mutation |
| Tyr 202 | Val 202 | engineered mutation |
| Met 221 | Lys 221 | engineered mutation |
| Asn 300 | Arg 288 | engineered mutation |
| - | Pro 289 | deletion |
| - | Asp 290 | deletion |
| - | Ala 291 | deletion |
| - | Phe 292 | deletion |
| - | Phe 293 | deletion |
| - | Gly 294 | deletion |
| - | Asp 295 | deletion |
| - | Pro 296 | deletion |
| - | Thr 297 | deletion |
| - | Arg 298 | deletion |
| - | Pro 299 | deletion |
| - | Ile 300 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25398.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 661.1 | |
| All* | Total formula weight | 26060.0 |
