6TVF
Crystal structure of the haemagglutinin from a H10N7 seal influenza virus isolated in Germany in complex with human receptor analogue, 6'-SLN
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G, I... (A, C, E, G, I...) | Hemagglutinin HA1 | polymer | 325 | 35499.1 | 6 | UniProt (A0A0A7HR51) Pfam (PF00509) | Influenza A virus | |
2 | B, D, F, H, J... (B, D, F, H, J...) | Hemagglutinin HA2 | polymer | 177 | 20313.4 | 6 | UniProt (A0A0A7HR51) Pfam (PF00509) | Influenza A virus | |
3 | M, P, R, U (M, P, R, U) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 4 | In PDB BIRD (PRD_900046) GlyTouCan (G73578JC) | 6'-sialyl-N-acetyllactosamine | ||
4 | N (N) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | branched | 471.4 | 1 | In PDB GlyTouCan (G63069TR) | |||
5 | O, Q, S, T, V (O, Q, S, T, V) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
6 | AA, BA, W (I, K, A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
7 | CA, X, Y (L, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
8 | Z (I) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 1 | Chemie (SIA) | |||
9 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K: 1 - 323 (UniProt: A0A0A7HR51)
B, D, F, H, J, L: 1 - 176 (UniProt: A0A0A7HR51)
PDB | External Database | Details |
---|---|---|
Asp -1 | - | expression tag |
Pro 0 | - | expression tag |
Gln 219 | Leu 228 | conflict |
PDB | External Database | Details |
---|---|---|
Lys 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 334874.8 | |
Branched | Number of molecules | 10 |
Total formula weight | 5291.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1093.1 | |
All* | Total formula weight | 341259.8 |