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6TVF

Crystal structure of the haemagglutinin from a H10N7 seal influenza virus isolated in Germany in complex with human receptor analogue, 6'-SLN

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G, I...
(A, C, E, G, I...)
Hemagglutinin HA1polymer32535499.16UniProt (A0A0A7HR51)
Pfam (PF00509)
Influenza A virus
2B, D, F, H, J...
(B, D, F, H, J...)
Hemagglutinin HA2polymer17720313.46UniProt (A0A0A7HR51)
Pfam (PF00509)
Influenza A virus
3M, P, R, U
(M, P, R, U)
N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched674.64In PDB
BIRD (PRD_900046)
GlyTouCan (G73578JC)
6'-sialyl-N-acetyllactosamine
4N
(N)
N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranosebranched471.41In PDB
GlyTouCan (G63069TR)
5O, Q, S, T, V
(O, Q, S, T, V)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.45In PDB
GlyTouCan (G42666HT)
6AA, BA, W
(I, K, A)
CALCIUM IONnon-polymer40.13Chemie (CA)
7CA, X, Y
(L, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
8Z
(I)
N-acetyl-alpha-neuraminic acidnon-polymer309.31Chemie (SIA)
9DA, EA, FA, GA, HA...
(A, B, C, D, E...)
waterwater18.0370Chemie (HOH)
Sequence modifications
A, C, E, G, I, K: 1 - 323 (UniProt: A0A0A7HR51)
PDBExternal DatabaseDetails
Asp -1-expression tag
Pro 0-expression tag
Gln 219Leu 228conflict
B, D, F, H, J, L: 1 - 176 (UniProt: A0A0A7HR51)
PDBExternal DatabaseDetails
Lys 177-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight334874.8
BranchedNumber of molecules10
Total formula weight5291.8
Non-Polymers*Number of molecules7
Total formula weight1093.1
All*Total formula weight341259.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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