6TVB
Crystal structure of the haemagglutinin from a transmissible H10N7 seal influenza virus isolated in Netherland in complex with human receptor analogue 6'-SLN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin HA1 | polymer | 325 | 35469.2 | 3 | UniProt (A0A0A7HR51) Pfam (PF00509) | Influenza A virus | |
| 2 | B, D, F (B, D, F) | Hemagglutinin HA2 | polymer | 177 | 20312.4 | 3 | UniProt (A0A0A7HR51) Pfam (PF00509) | Influenza A virus | |
| 3 | G, H, I (G, H, I) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 3 | In PDB BIRD (PRD_900046) GlyTouCan (G73578JC) | 6'-sialyl-N-acetyllactosamine | ||
| 4 | AA, BA, CA, J, K... (F, A, B, C, D...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
| 5 | L, M, X (B, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 1211 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 323 (UniProt: A0A0A7HR51)
B, D, F: 1 - 176 (UniProt: A0A0A7HR51)
| PDB | External Database | Details |
|---|---|---|
| Asp -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Lys 96 | Glu 105 | conflict |
| Ser 205 | Asn 214 | conflict |
| Ile 237 | Thr 246 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asn 158 | Asp 490 | conflict |
| Lys 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 167344.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2023.8 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1718.8 | |
| All* | Total formula weight | 171087.4 |
