6TVA
Crystal structure of the haemagglutinin from a transmissible H10N7 seal influenza virus isolated in Netherland in complex with avian receptor analogue, 3'-SLN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Haemagglutinin HA1 | polymer | 320 | 34914.5 | 3 | UniProt (A0A0A7HR51) Pfam (PF00509) In PDB | Influenza A virus | |
| 2 | B, D, F | Haemagglutinin HA2 | polymer | 172 | 19759.7 | 3 | UniProt (A0A0A7HR51) Pfam (PF00509) In PDB | Influenza A virus | |
| 3 | G, H, J | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 3 | In PDB BIRD (PRD_900067) GlyTouCan (G00065MO) | 3'-sialyl-N-acetyllactosamine | ||
| 4 | I | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 5 | A, B, D, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 6 | water | water | 18.0 | 1182 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 318 (UniProt: A0A0A7HR51)
B, D, F: 1 - 172 (UniProt: A0A0A7HR51)
| PDB | External Database | Details |
|---|---|---|
| Asp -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Lys 96 | Glu 105 | conflict |
| Ser 205 | Asn 214 | conflict |
| Ile 237 | Thr 246 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asn 158 | Asp 490 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 164022.8 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2934.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 168063.5 |
