6TN5
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Heat shock protein HSP 90-alpha | polymer | 230 | 25926.1 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (Human) | Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
2 | AAA | ~{N}-(4-aminocarbonylphenyl)-~{N}-methyl-2,4-bis(oxidanyl)benzamide | non-polymer | 286.3 | 1 | Chemie (NL8) | |||
3 | AAA | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence modifications
AAA: 9 - 236 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
His 7 | - | expression tag |
Met 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 25926.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 321.7 | |
All* | Total formula weight | 26247.8 |