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6TMH

Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, OSCP/F1/c-ring model

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(i)
Inhibitor of F1polymer14516167.51UniProt (A0A125YJP2)Toxoplasma gondii (strain ATCC 50853 / GT1)
2B, C, D
(A, E, C)
ATP synthase subunit alpha,subunit alphapolymer56561189.23UniProt (S7UU80)
Pfam (PF02874)
Pfam (PF00006)
Pfam (PF00306)
Toxoplasma gondii (strain ATCC 50853 / GT1)
3E, F, G
(B, F, D)
ATP synthase subunit betapolymer56059983.33UniProt (A0A125YYY4)
Pfam (PF02874)
Pfam (PF00006)
Pfam (PF22919)
Toxoplasma gondii (strain ATCC 50853 / GT1)
4H
(g)
ATP synthase subunit gammapolymer31434573.01UniProt (A0A125YUH0)
Pfam (PF00231)
Toxoplasma gondii (strain ATCC 50853 / GT1)
5I
(d)
ATP synthase subunit deltapolymer18319476.11UniProt (A0A125YRE2)
Pfam (PF02823)
Toxoplasma gondii (strain ATCC 50853 / GT1)
6J
(e)
ATP synthase subunit epsilonpolymer738492.71UniProt (S7VV10)
Pfam (PF04627)
Toxoplasma gondii (strain ATCC 50853 / GT1)
7K
(G)
Oligomycin sensitivity conferring protein (OSCP)polymer25227670.01UniProt (A0A125YKF8)
Pfam (PF00213)
Toxoplasma gondii (strain ATCC 50853 / GT1)
8L, M, N, O, P...
(H, I, J, K, L...)
subunit cpolymer16617753.510UniProt (A0A125YJV2)
Pfam (PF00137)
Toxoplasma gondii (strain ATCC 50853 / GT1)
9V, X, Z
(A, E, C)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.23Chemie (ATP)
10AA, CA, EA, W, Y
(C, B, D, A, E)
MAGNESIUM IONnon-polymer24.35Chemie (MG)
11BA, DA
(B, D)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
Sequence modifications
A, E, C: 1 - 538 (UniProt: S7UU80)
A, E, C: 539 - 565 (PDB: 6TMH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains21
Total formula weight647431.8
Non-Polymers*Number of molecules10
Total formula weight2497.5
All*Total formula weight649929.2
*Water molecules are not included.

245011

PDB entries from 2025-11-19

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