6TKV
Crystal structure of the human FUT8 in complex with GDP and a biantennary complex N-glycan
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-(1,6)-fucosyltransferase | polymer | 468 | 53966.0 | 1 | UniProt (Q9BYC5) Pfam (PF19745) Pfam (PF14604) | Homo sapiens (Human) | Alpha1-6FucT,Fucosyltransferase 8,GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase,GDP-fucose--glycoprotein fucosyltransferase,Glycoprotein 6-alpha-L-fucosyltransferase |
| 2 | B (B) | Alpha-(1,6)-fucosyltransferase | polymer | 453 | 52319.4 | 1 | UniProt (Q9BYC5) Pfam (PF19745) Pfam (PF14604) | Homo sapiens (Human) | Alpha1-6FucT,Fucosyltransferase 8,GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase,GDP-fucose--glycoprotein fucosyltransferase,Glycoprotein 6-alpha-L-fucosyltransferase |
| 3 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1317.2 | 2 | In PDB GlyTouCan (G39213VZ) | |||
| 4 | E, J (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 5 | F, G, H, I, K... (A, B) | GLYCEROL | non-polymer | 92.1 | 17 | Chemie (GOL) | |||
| 6 | X, Y (A, B) | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
B: 108 - 575 (UniProt: Q9BYC5)
| PDB | External Database | Details |
|---|---|---|
| - | Asn 430 | deletion |
| - | Ser 431 | deletion |
| - | Ile 432 | deletion |
| - | Ser 433 | deletion |
| - | Trp 434 | deletion |
| - | Ser 435 | deletion |
| - | Ala 436 | deletion |
| - | Gly 437 | deletion |
| - | Leu 438 | deletion |
| - | His 439 | deletion |
| - | Asn 440 | deletion |
| - | Arg 441 | deletion |
| - | Tyr 442 | deletion |
| - | Thr 443 | deletion |
| - | Glu 444 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 106285.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2634.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2452.0 | |
| All* | Total formula weight | 111371.8 |
