6TIZ
DROSOPHILA GDP-TUBULIN Y222F MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1 chain | polymer | 450 | 49989.3 | 2 | UniProt (P06603) Pfam (PF00091) Pfam (PF03953) | Drosophila melanogaster (Fruit fly) | |
| 2 | B, D (B, D) | Tubulin beta-1 chain | polymer | 447 | 50178.1 | 2 | UniProt (Q24560) Pfam (PF00091) Pfam (PF03953) | Drosophila melanogaster (Fruit fly) | Beta-1-tubulin |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16851.1 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Norway rat) | Stathmin-like protein B3,RB3 |
| 4 | F, P (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | G, Q (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | H, I, J, N, O... (A, B, C, D, E) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 7 | K, L (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 8 | M, U (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 9 | AA, BA, CA, DA, EA (A, B, C, D, E) | water | water | 18.0 | 759 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 450 (UniProt: P06603)
B, D: 1 - 447 (UniProt: Q24560)
E: 4 - 145 (UniProt: P63043)
| PDB | External Database | Details |
|---|---|---|
| Arg 40 | Lys 40 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Phe 222 | Tyr 222 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Ala 4 | Ser 48 | engineered mutation |
| Ala 14 | Cys 58 | engineered mutation |
| Trp 20 | Phe 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 217185.9 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3414.4 | |
| All* | Total formula weight | 220600.3 |
