6TIY

DROSOPHILA GMPCPP-TUBULIN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Tubulin alpha-1 chain	polymer	450	49989.3	2	UniProt (P06603) Pfam (PF00091) Pfam (PF03953)	Drosophila melanogaster (Fruit fly)
2	B, D (B, D)	Tubulin beta-1 chain	polymer	447	50194.1	2	UniProt (Q24560) Pfam (PF00091) Pfam (PF03953)	Drosophila melanogaster (Fruit fly)	Beta-1-tubulin
3	E (E)	Stathmin-4	polymer	143	16851.1	1	UniProt (P63043) Pfam (PF00836)	Rattus norvegicus (Rat)	Stathmin-like protein B3,RB3
4	F, P (A, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)
5	G, M, Q, U (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG) PubChem (888)
6	H, I, J, N, O... (A, B, C, D, E)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
7	K (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL) PubChem (753)
8	L, T (B, D)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	2	Chemie (G2P)
9	AA, BA, CA, DA, Z (B, C, D, E, A)	water	water		18.0	430	Chemie (HOH)

Sequence modifications

A, C: 1 - 450 (UniProt: P06603)

PDB	External Database	Details
Arg 40	Lys 40	engineered mutation

E: 4 - 145 (UniProt: P63043)

PDB	External Database	Details
Met 3	-	initiating methionine
Ala 4	Ser 48	engineered mutation
Ala 14	Cys 58	engineered mutation
Trp 20	Phe 64	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	217217.9
Non-Polymers*	Number of molecules	20
	Total formula weight	3334.8
All*	Total formula weight	220552.7

*Water molecules are not included.