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6TI1

SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with PLP/L-Threonine/Lys230 gem diamine complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, C)
Serine hydroxymethyltransferasepolymer41645061.92UniProt (Q5MCK9)
Pfam (PF00464)
UniProt (by SIFTS) (Q5M0B4)
Streptococcus thermophilusSerine methylase
2C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3D, F
(A, C)
N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threoninenon-polymer350.32Chemie (2BO)
4E
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5G, H
(A, C)
waterwater18.0374Chemie (HOH)
Sequence modifications
A, C: 1 - 416 (UniProt: Q5MCK9)
PDBExternal DatabaseDetails
Ser 55Tyr 55engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight90123.9
Non-Polymers*Number of molecules4
Total formula weight815.6
All*Total formula weight90939.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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