6THP
Neprilysin in complex with the inhibitor (R)-4-(1-carboxy-3-(3'-chlorobiphenyl-4-yl)propan-2-ylamino)-4-oxobutanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Neprilysin | polymer | 696 | 79525.5 | 2 | UniProt (P08473) Pfam (PF05649) Pfam (PF01431) In PDB | Homo sapiens (Human) | Atriopeptidase,Common acute lymphocytic leukemia antigen,CALLA,Enkephalinase,Neutral endopeptidase 24.11,Neutral endopeptidase,Skin fibroblast elastase,SFE |
| 2 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, B | 4-[[(2~{R})-1-[4-(3-chlorophenyl)phenyl]-4-oxidanyl-4-oxidanylidene-butan-2-yl]amino]-4-oxidanylidene-butanoic acid | non-polymer | 389.8 | 2 | Chemie (N9Q) | |||
| 5 | water | water | 18.0 | 352 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 159051.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2680.1 | |
| All* | Total formula weight | 161731.2 |
