6T9W
Crystal structure of formate dehydrogenase FDH2 D222A/Q223R enzyme from Granulicella mallensis MP5ACTX8 in complex with NADP and azide.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, A, C, D) | Formate dehydrogenase | polymer | 386 | 42574.6 | 4 | UniProt (G8NTI5) Pfam (PF00389) Pfam (PF02826) | Granulicella mallensis MP5ACTX8 | FDH,NAD-dependent formate dehydrogenase |
| 2 | E, G, I (B, A, C) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 3 | Chemie (NAP) | |||
| 3 | F, H, J (B, A, C) | AZIDE ION | non-polymer | 42.0 | 3 | Chemie (AZI) | |||
| 4 | K, L, M, N (B, A, C, D) | water | water | 18.0 | 745 | Chemie (HOH) |
Sequence modifications
B, A, C, D: 1 - 386 (UniProt: G8NTI5)
| PDB | External Database | Details |
|---|---|---|
| Ala 222 | Asp 222 | engineered mutation |
| Arg 223 | Gln 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170298.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2356.3 | |
| All* | Total formula weight | 172654.8 |
