6T7Z
KEAP1 IN COMPLEX WITH COMPOUND 44
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kelch-like ECH-associated protein 1 | polymer | 293 | 31951.8 | 1 | UniProt (Q14145) Pfam (PF01344) | Homo sapiens (human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | B (B) | ACE-CYS-ASA-4FB-GLU-THR-GLY-GLU-CYS-NH2 | polymer | 10 | 894.9 | 1 | synthetic construct | ||
| 3 | C, D, E, F (A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A: 321 - 609 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Gly 317 | - | expression tag |
| Ser 318 | - | expression tag |
| His 319 | - | expression tag |
| Met 320 | - | expression tag |
| Ala 540 | Glu 540 | conflict |
| Ala 542 | Glu 542 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32846.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 236.2 | |
| All* | Total formula weight | 33082.9 |
