6T7P
human plasmakallikrein protease domain in complex with active site directed inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Plasma kallikrein | polymer | 242 | 27187.0 | 1 | UniProt (P03952) Pfam (PF00089) | Homo sapiens (Human) | Fletcher factor,Kininogenin,Plasma prekallikrein,PKK |
| 2 | B (A) | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 3 | C, D, E, F, G... (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 10 | Chemie (DMS) | |||
| 4 | M (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | N (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | O (A) | (2~{S},4~{R})-1-[[(3~{S})-3-azanyl-2,3-dihydro-1-benzofuran-6-yl]carbonyl]-~{N}-(3-chlorophenyl)-4-phenyl-pyrrolidine-2-carboxamide | non-polymer | 461.9 | 1 | Chemie (MU8) | |||
| 7 | P (A) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27187.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1737.7 | |
| All* | Total formula weight | 28924.6 |
