Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue GSH A 301 |
| Chain | Residue |
| A | TRP29 |
| A | HOH407 |
| A | HOH414 |
| A | HOH415 |
| A | HOH433 |
| A | HOH503 |
| A | HOH561 |
| A | PRO60 |
| A | GLN62 |
| A | GLU87 |
| A | ILE88 |
| A | PRO120 |
| A | CYS122 |
| A | MET206 |
| A | TRP207 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 302 |
| Chain | Residue |
| A | GLY69 |
| A | THR115 |
| A | PHE117 |
| A | HOH475 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 303 |
| Chain | Residue |
| A | TRP24 |
| A | ASN159 |
| A | TYR184 |
| A | HOH410 |
| A | HOH574 |
| A | HOH588 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 304 |
| Chain | Residue |
| A | ASP63 |
| A | TRP65 |
| A | ARG65 |
| A | GLN84 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 305 |
| Chain | Residue |
| A | GLN34 |
| A | GLN38 |
| A | LEU73 |
| A | ILE76 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 306 |
| Chain | Residue |
| A | GLY25 |
| A | TRP27 |
| A | ILE70 |
| A | LEU71 |
| A | PHE117 |
| A | LEU155 |
| A | HOH520 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 307 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 308 |
| Chain | Residue |
| A | GLU150 |
| A | ILE151 |
| A | GLN152 |
| A | ASN153 |
| A | HOH466 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 309 |
| Chain | Residue |
| A | TYR184 |
| A | GLY187 |
| A | LYS188 |
| A | HOH525 |
| A | HOH633 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 310 |
| Chain | Residue |
| A | LYS126 |
| A | ALA232 |
| A | GLU233 |
| A | TYR234 |
| A | MET235 |
| A | ASP236 |
| A | HOH544 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 311 |
| Chain | Residue |
| A | SER74 |
| A | LYS202 |
| A | HIS203 |
| A | ASN204 |
| A | HOH406 |
| A | HOH477 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 312 |
| Chain | Residue |
| A | HIS91 |
| A | GLN92 |
| A | ARG179 |
| A | TRP237 |
| A | HOH449 |
| A | HOH544 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 313 |
| Chain | Residue |
| A | GLU26 |
| A | TRP27 |
| A | TRP137 |
| A | LYS157 |
| A | HOH401 |
| A | HOH510 |
| A | HOH583 |
| site_id | AD5 |
| Number of Residues | 19 |
| Details | binding site for residue MU8 A 314 |
| Chain | Residue |
| A | HIS40 |
| A | LEU41 |
| A | HIS57 |
| A | PHE143 |
| A | ASP189 |
| A | ALA190 |
| A | CYS191 |
| A | LYS192 |
| A | GLY193 |
| A | SER195 |
| A | THR213 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | CYS220 |
| A | HOH448 |
| A | HOH454 |
| A | HOH580 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| Chain | Residue | Details |
| A | ASN21 | |
| A | ASN113 | |
| Chain | Residue | Details |
| A | ASN72 | |
