6T6J
Crystal Structure of the C-terminal domain of the HIV-1 Integrase (subtype A2, mutant N254K, K340Q)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Pol protein | polymer | 59 | 7053.2 | 3 | UniProt (A0A290WA76) Pfam (PF00552) UniProt (by SIFTS) (Q75002) | Human immunodeficiency virus 1 | |
| 2 | D, E (A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 3 | F, G, H (A, B, C) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B, C: 219 - 270 (UniProt: A0A290WA76)
| PDB | External Database | Details |
|---|---|---|
| Met 212 | - | initiating methionine |
| Gly 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| Gln 240 | Lys 241 | engineered mutation |
| Lys 254 | Asn 255 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 21159.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 117.4 | |
| All* | Total formula weight | 21276.9 |
