6T26

X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Alkaline phosphatase	polymer	512	56626.1	2	UniProt (Q93P54) Pfam (PF00245)	Vibrio sp. G15-21
2	C, D, N, O (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	E, L, M, P, W... (A, B)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	F, G, H, Q, R... (A, B)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
5	I, T (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
6	J, K, U, V (A, B)	CYCLOHEXYLAMMONIUM ION	non-polymer		100.2	4	Chemie (HAI)
7	Y, Z (A, B)	water	water		18.0	411	Chemie (HOH)

Sequence modifications

A, B: 1 - 502 (UniProt: Q93P54)

PDB	External Database	Details
Ser 503	-	expression tag
Ala 504	-	expression tag
Trp 505	-	expression tag
Ser 506	-	expression tag
His 507	-	expression tag
Pro 508	-	expression tag
Gln 509	-	expression tag
Phe 510	-	expression tag
Glu 511	-	expression tag
Lys 512	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	113252.2
Non-Polymers*	Number of molecules	22
	Total formula weight	1210.9
All*	Total formula weight	114463.0

*Water molecules are not included.