6T0K
Crystal structure of CYP124 in complex with inhibitor carbethoxyhexyl imidazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYP124 in complex with inhibitor carbethoxyhexyl imidazole | polymer | 435 | 48838.9 | 1 | UniProt (P9WPP3) Pfam (PF00067) | Mycobacterium tuberculosis H37Rv | |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | ethyl 7-imidazol-1-ylheptanoate | non-polymer | 224.3 | 1 | Chemie (M65) | |||
| 4 | D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | H, I (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | K (A) | water | water | 18.0 | 665 | Chemie (HOH) |
Sequence modifications
A: 1 - 428 (UniProt: P9WPP3)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48838.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1293.2 | |
| All* | Total formula weight | 50132.2 |
