6T0H
Crystal structure of CYP124 in complex with 1-alpha-hydroxy-vitamin D3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYP124 in complex with inhibitor carbethoxyhexyl imidazole | polymer | 435 | 48838.9 | 1 | UniProt (P9WPP3) Pfam (PF00067) | Mycobacterium tuberculosis H37Rv | |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 1-alpha-hydroxy-vitamin D3 | non-polymer | 400.6 | 1 | Chemie (M9B) | |||
| 4 | D, E, H, M (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | F, G, I, J, K... (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 6 | Chemie (PGE) | |||
| 6 | N, O (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | P, Q, R (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 8 | S (A) | water | water | 18.0 | 725 | Chemie (HOH) |
Sequence modifications
A: 1 - 428 (UniProt: P9WPP3)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48838.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2441.5 | |
| All* | Total formula weight | 51280.4 |
