6T0H
Crystal structure of CYP124 in complex with 1-alpha-hydroxy-vitamin D3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYP124 in complex with inhibitor carbethoxyhexyl imidazole | polymer | 435 | 48838.9 | 1 | UniProt (P9WPP3) Pfam (PF00067) | Mycobacterium tuberculosis H37Rv | |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 1-alpha-hydroxy-vitamin D3 | non-polymer | 400.6 | 1 | Chemie (M9B) PubChem (20838260) PubChem (21958049) PubChem (176541409) PubChem (24003349) PubChem (25056913) PubChem (29920482) PubChem (42609152) PubChem (38838) PubChem (46780105) PubChem (53487908) PubChem (54069152) PubChem (54147293) PubChem (54147294) PubChem (54147295) PubChem (54147296) PubChem (54147297) PubChem (57345787) PubChem (45073394) PubChem (59760987) PubChem (443990) PubChem (66509212) PubChem (71401276) PubChem (57369692) PubChem (73707426) PubChem (73707490) PubChem (78358013) PubChem (59919877) PubChem (3049977) PubChem (87091364) PubChem (87382319) PubChem (87403352) PubChem (87899157) PubChem (87899158) PubChem (88200941) PubChem (88359422) PubChem (88592660) PubChem (2091) PubChem (90850912) PubChem (5282181) PubChem (5283717) PubChem (5283720) PubChem (5283721) PubChem (5283722) PubChem (5283723) PubChem (5284515) PubChem (73265251) PubChem (91307431) PubChem (91405987) PubChem (5283718) PubChem (5283719) PubChem (98116097) PubChem (99722619) PubChem (124604902) PubChem (6390505) PubChem (6434322) PubChem (92852870) PubChem (93602443) PubChem (98116096) PubChem (134688803) PubChem (135022889) PubChem (135391135) PubChem (124225805) PubChem (124386085) PubChem (124425589) PubChem (11661297) PubChem (11668478) PubChem (124567689) PubChem (124584046) PubChem (124650995) PubChem (13019633) PubChem (13019634) PubChem (13019645) PubChem (124825668) PubChem (155982230) PubChem (165428957) PubChem (168498987) PubChem (129010229) PubChem (173367497) PubChem (173519236) PubChem (129396776) PubChem (129681545) PubChem (134694392) PubChem (134814131) PubChem (139423927) PubChem (145705666) PubChem (145705856) PubChem (162489849) PubChem (163285106) PubChem (164576788) PubChem (168322775) PubChem (171153531) PubChem (171156750) PubChem (171378655) PubChem (171397566) | |||
| 4 | D, E, H, M (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 5 | F, G, I, J, K... (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 6 | Chemie (PGE) | |||
| 6 | N, O (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 7 | P, Q, R (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 8 | S (A) | water | water | 18.0 | 725 | Chemie (HOH) |
Sequence modifications
A: 1 - 428 (UniProt: P9WPP3)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48838.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2441.5 | |
| All* | Total formula weight | 51280.4 |
