6T0H

Crystal structure of CYP124 in complex with 1-alpha-hydroxy-vitamin D3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006707	biological_process	cholesterol catabolic process
A	0008395	molecular_function	steroid hydroxylase activity
A	0010430	biological_process	fatty acid omega-oxidation
A	0016491	molecular_function	oxidoreductase activity
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0020037	molecular_function	heme binding
A	0031073	molecular_function	cholesterol 26-hydroxylase activity
A	0036199	molecular_function	cholest-4-en-3-one 26-monooxygenase activity
A	0046872	molecular_function	metal ion binding
A	0070402	molecular_function	NADPH binding
A	0097089	biological_process	methyl-branched fatty acid metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"19933331","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WM5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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