6T0B
The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, K (A, L) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 431 | 47459.3 | 2 | UniProt (P07256) Pfam (PF00675) Pfam (PF05193) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 1,Core protein I,Ubiquinol-cytochrome-c reductase complex core protein 1 |
| 2 | B, L (B, M) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 352 | 38751.9 | 2 | UniProt (P07257) Pfam (PF00675) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 2,Core protein II,Ubiquinol-cytochrome-c reductase complex core protein 2 |
| 3 | C, M (C, N) | Cytochrome b | polymer | 385 | 43686.6 | 2 | UniProt (P00163) Pfam (PF00033) Pfam (PF00032) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 3,Complex III subunit CYTB,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Cytochrome b-c1 complex subunit CYTB,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit |
| 4 | D, N (D, O) | Cytochrome c1, heme protein, mitochondrial | polymer | 248 | 27807.4 | 2 | UniProt (P07143) Pfam (PF02167) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 4,Complex III subunit IV,Cytochrome b-c1 complex subunit 4,Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit,Cytochrome c-1 |
| 5 | E, O (E, P) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 185 | 20123.0 | 2 | UniProt (P08067) Pfam (PF02921) Pfam (PF00355) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 5,Rieske iron-sulfur protein,RISP,Ubiquinol-cytochrome c reductase iron-sulfur subunit |
| 6 | F, P (F, Q) | Cytochrome b-c1 complex subunit 6 | polymer | 147 | 17276.1 | 2 | UniProt (P00127) Pfam (PF02320) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 6,Complex III subunit VI,Cytochrome c1 non-heme 17 kDa protein,Mitochondrial hinge protein,Ubiquinol-cytochrome c reductase complex 17 kDa protein |
| 7 | G, Q (G, R) | Cytochrome b-c1 complex subunit 7 | polymer | 127 | 14583.8 | 2 | UniProt (P00128) Pfam (PF02271) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 7,Complex III subunit VII,Ubiquinol-cytochrome c reductase c reductase complex 14 kDa protein |
| 8 | H, R (H, S) | Cytochrome b-c1 complex subunit 8 | polymer | 94 | 10987.5 | 2 | UniProt (P08525) Pfam (PF02939) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 8,Complex III subunit VII,Ubiquinol-cytochrome c reductase complex 11 kDa protein,Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C |
| 9 | I, S (I, T) | Cytochrome b-c1 complex subunit 9 | polymer | 66 | 7485.3 | 2 | UniProt (P22289) Pfam (PF05365) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 9,Complex III subunit X,Cytochrome c1 non-heme 7.3 kDa protein,Ubiquinol-cytochrome c reductase complex 7.3 kDa protein |
| 10 | J, T (J, U) | Cytochrome b-c1 complex subunit 10 | polymer | 77 | 8602.9 | 2 | UniProt (P37299) Pfam (PF09796) | Saccharomyces cerevisiae S288c (Baker's yeast) | Complex III subunit 10,Complex III subunit XI,Ubiquinol-cytochrome c reductase complex 8.5 kDa protein |
| 11 | HA, U (a, n) | Cytochrome c oxidase subunit 1 | polymer | 534 | 58832.6 | 2 | UniProt (P00401) Pfam (PF00115) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide I |
| 12 | IA, V (b, o) | Cytochrome c oxidase subunit 2 | polymer | 236 | 26779.8 | 2 | UniProt (P00410) Pfam (PF02790) Pfam (PF00116) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide II |
| 13 | JA, W (c, p) | Cytochrome c oxidase subunit 3 | polymer | 269 | 30383.6 | 2 | UniProt (P00420) Pfam (PF00510) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide III |
| 14 | KA, X (d, q) | Cytochrome c oxidase subunit 4, mitochondrial | polymer | 130 | 14188.9 | 2 | UniProt (P04037) Pfam (PF01215) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide IV |
| 15 | LA, Y (e, r) | Cytochrome c oxidase polypeptide 5B, mitochondrial | polymer | 134 | 15325.4 | 2 | UniProt (P00425) Pfam (PF02936) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide Vb |
| 16 | MA, Z (f, s) | Cytochrome c oxidase subunit 6, mitochondrial | polymer | 108 | 12642.0 | 2 | UniProt (P00427) Pfam (PF02284) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide VI |
| 17 | AA, NA (g, t) | Cytochrome c oxidase subunit 7 | polymer | 59 | 6811.2 | 2 | UniProt (P10174) Pfam (PF02238) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide VII |
| 18 | BA, OA (h, u) | Cytochrome c oxidase polypeptide VIII, mitochondrial | polymer | 51 | 5737.7 | 2 | UniProt (P04039) Pfam (PF02935) | Saccharomyces cerevisiae S288c (Baker's yeast) | |
| 19 | CA, PA (i, v) | Cytochrome c oxidase subunit 7A | polymer | 55 | 6471.7 | 2 | UniProt (P07255) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide VIIA |
| 20 | DA, QA (j, w) | Cytochrome c oxidase subunit 6B | polymer | 82 | 9668.7 | 2 | UniProt (Q01519) Pfam (PF02297) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide VIb |
| 21 | EA, RA (k, x) | Cytochrome c oxidase subunit 6A, mitochondrial | polymer | 131 | 15117.0 | 2 | UniProt (P32799) Pfam (PF02046) | Saccharomyces cerevisiae S288c (Baker's yeast) | Cytochrome c oxidase polypeptide VIa |
| 22 | FA, SA (l, y) | Cox26 | polymer | 66 | 7461.7 | 2 | UniProt (Q2V2P9) | Saccharomyces cerevisiae S288c (Baker's yeast) | |
| 23 | GA, TA (m, z) | Respiratory supercomplex factor 2, mitochondrial | polymer | 224 | 25381.1 | 2 | UniProt (P53721) Pfam (PF04588) | Saccharomyces cerevisiae S288c (Baker's yeast) | Altered inheritance of mitochondria protein 38 |
| 24 | DB, IB, NB, RB, SB... (D, H, L, N, A...) | CARDIOLIPIN | non-polymer | 1464.0 | 8 | Chemie (CDL) | |||
| 25 | AB, AC, AD, BD, DD... (C, S, o, p, r...) | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE | non-polymer | 692.0 | 26 | Chemie (PEF) | |||
| 26 | PB, QB, WA, XA (N, C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 27 | BB, BC, ED, KB, LB... (C, T, r, H, I...) | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE | non-polymer | 734.0 | 7 | Chemie (PCF) | |||
| 28 | CB, WB (D, O) | HEME C | non-polymer | 618.5 | 2 | Chemie (HEC) | |||
| 29 | EB, YB (E, P) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 30 | CC, RC (a, n) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 31 | DC, EC, SC, TC (a, n) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 32 | FC, UC (a, n) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 33 | GC, VC (a, n) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 34 | IC, ZC (b, o) | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) | |||
| 35 | CD, NC (q, d) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
k, x: 10 - 129 (UniProt: P32799)
| PDB | External Database | Details |
|---|---|---|
| Gly 130 | - | expression tag |
| Ala 131 | - | expression tag |
| Arg 132 | - | expression tag |
| Gly 133 | - | expression tag |
| Ser 134 | - | expression tag |
| His 135 | - | expression tag |
| His 136 | - | expression tag |
| His 137 | - | expression tag |
| His 138 | - | expression tag |
| His 139 | - | expression tag |
| His 140 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 46 |
| Total formula weight | 943130.5 | |
| Non-Polymers* | Number of molecules | 63 |
| Total formula weight | 42948.4 | |
| All* | Total formula weight | 986078.8 |
