6SZP

High resolution crystal structure of human DDAH-1 in complex with N-(4-Aminobutyl)-N'-(2-Methoxyethyl)guanidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	polymer	297	32568.3	1	UniProt (O94760) Pfam (PF19420)	Homo sapiens (Human)	Dimethylarginine dimethylaminohydrolase 1,DDAHI,Dimethylargininase-1
2	B (A)	(1~{S})-~{N}'-(4-azanylbutyl)-~{N}"-(2-methoxyethyl)methanetriamine	non-polymer		190.3	1	Chemie (M3B)
3	C, D (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	E (A)	water	water		18.0	137	Chemie (HOH)

Sequence modifications

A: 1 - 285 (UniProt: O94760)

PDB	External Database	Details
Met -11	-	initiating methionine
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	32568.3
Non-Polymers*	Number of molecules	3
	Total formula weight	374.5
All*	Total formula weight	32942.8

*Water molecules are not included.