6SVM
Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate, L-Glu, and UDP-GalNAc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | polymer | 687 | 77696.0 | 2 | UniProt (Q06210) Pfam (PF13522) Pfam (PF01380) | Homo sapiens (Human) | D-fructose-6-phosphate amidotransferase 1,Glutamine:fructose-6-phosphate amidotransferase 1,GFAT1,Hexosephosphate aminotransferase 1 |
| 2 | C, G (A, B) | GLUCOSE-6-PHOSPHATE | non-polymer | 260.1 | 2 | Chemie (G6Q) PubChem (20831679) PubChem (25323050) PubChem (44229174) PubChem (18603327) PubChem (99058) PubChem (3034788) PubChem (3034794) PubChem (51404088) PubChem (51404090) PubChem (439958) PubChem (87305227) PubChem (87891597) PubChem (88507758) PubChem (88508138) PubChem (85187) PubChem (5459942) PubChem (5460110) PubChem (6101690) PubChem (13179156) PubChem (13179157) | |||
| 3 | D (A) | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 4 | E, H (A, B) | URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE | non-polymer | 607.4 | 2 | Chemie (UD2) | |||
| 5 | F, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 681 (UniProt: Q06210)
| PDB | External Database | Details |
|---|---|---|
| His 299 | - | insertion |
| His 299 | - | insertion |
| His 299 | - | insertion |
| His 299 | - | insertion |
| His 299 | - | insertion |
| His 299 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 155392.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1930.7 | |
| All* | Total formula weight | 157322.7 |
