6SS4
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021181
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Arginase-2, mitochondrial | polymer | 339 | 37084.9 | 1 | UniProt (P78540) Pfam (PF00491) | Homo sapiens (Human) | Arginase II,Kidney-type arginase,Non-hepatic arginase,Type II arginase |
| 2 | B (HHH) | Fab C0021181 heavy chain (IgG1) | polymer | 233 | 24819.8 | 1 | Homo sapiens (Human) | ||
| 3 | C (LLL) | Fab C0021181 light chain (IgG1) | polymer | 220 | 23124.5 | 1 | Homo sapiens (Human) | ||
| 4 | D, E (AAA) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | F (AAA) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) |
Sequence modifications
AAA: 23 - 354 (UniProt: P78540)
| PDB | External Database | Details |
|---|---|---|
| Met 22 | - | initiating methionine |
| His 355 | - | expression tag |
| His 356 | - | expression tag |
| His 357 | - | expression tag |
| His 358 | - | expression tag |
| His 359 | - | expression tag |
| His 360 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 85029.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 204.8 | |
| All* | Total formula weight | 85234.0 |
