6SRF
Crystal Structure of Human Prolidase G278N variant expressed in the presence of chaperones
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Xaa-Pro dipeptidase | polymer | 488 | 54227.6 | 2 | UniProt (P12955) Pfam (PF05195) Pfam (PF00557) | Homo sapiens (Human) | X-Pro dipeptidase,Imidodipeptidase,Peptidase D,Proline dipeptidase,Prolidase |
| 2 | C, H (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, I (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F, J (A, B) | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) | |||
| 6 | G, K (A, B) | PROLINE | non-polymer | 115.1 | 2 | Chemie (PRO) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 1034 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 493 (UniProt: P12955)
| PDB | External Database | Details |
|---|---|---|
| Asp 278 | Gly 278 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 108455.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 628.3 | |
| All* | Total formula weight | 109083.4 |
