6SQ2
Structure of a phosphomimetic switch 2 variant of Rab8a in complex with the phospho-Rab binding domain of RILPL2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ras-related protein Rab-8A | polymer | 184 | 21077.2 | 2 | UniProt (P61006) Pfam (PF00071) In PDB | Homo sapiens (Human) | Oncogene c-mel |
2 | D, E | RILP-like protein 2 | polymer | 43 | 5296.0 | 2 | UniProt (Q969X0) Pfam (PF11461) In PDB | Homo sapiens (Human) | Rab-interacting lysosomal protein-like 2,p40phox-binding protein |
3 | A, B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | water | water | 18.0 | 513 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 181 (UniProt: P61006)
D, E: 129 - 165 (UniProt: Q969X0)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Leu 67 | Gln 67 | engineered mutation |
Glu 72 | Thr 72 | engineered mutation |
PDB | External Database | Details |
---|---|---|
His 123 | - | expression tag |
His 124 | - | expression tag |
His 125 | - | expression tag |
His 126 | - | expression tag |
His 127 | - | expression tag |
His 128 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 52746.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1095.0 | |
All* | Total formula weight | 53841.4 |