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6SQ2

Structure of a phosphomimetic switch 2 variant of Rab8a in complex with the phospho-Rab binding domain of RILPL2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BRas-related protein Rab-8Apolymer18421077.22UniProt (P61006)
Pfam (PF00071)
In PDB
Homo sapiens (Human)Oncogene c-mel
2D, ERILP-like protein 2polymer435296.02UniProt (Q969X0)
Pfam (PF11461)
In PDB
Homo sapiens (Human)Rab-interacting lysosomal protein-like 2,p40phox-binding protein
3A, BGUANOSINE-5'-TRIPHOSPHATEnon-polymer523.22Chemie (GTP)
4A, BMAGNESIUM IONnon-polymer24.32Chemie (MG)
5waterwater18.0513Chemie (HOH)
Sequence modifications
A, B: 1 - 181 (UniProt: P61006)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Leu 67Gln 67engineered mutation
Glu 72Thr 72engineered mutation
D, E: 129 - 165 (UniProt: Q969X0)
PDBExternal DatabaseDetails
His 123-expression tag
His 124-expression tag
His 125-expression tag
His 126-expression tag
His 127-expression tag
His 128-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight52746.4
Non-Polymers*Number of molecules4
Total formula weight1095.0
All*Total formula weight53841.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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