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6SM5

MbC/SHP1-C-SH2 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 6polymer12013252.91UniProt (P29350)
Pfam (PF00017)
Homo sapiens (Human)Hematopoietic cell protein-tyrosine phosphatase,Protein-tyrosine phosphatase 1C,PTP-1C,Protein-tyrosine phosphatase SHP-1,SH-PTP1
2B
(B)
MbC (monobody targeting SHP1-C-SH2)polymer9310012.01synthetic construct
3C, D
(A, B)
waterwater18.021Chemie (HOH)
Sequence modifications
A: 3 - 117 (UniProt: P29350)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
Lys 118-expression tag
Glu 119-expression tag
Lys 120-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight23264.9
All*Total formula weight23264.9
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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