6SLM
Crystal structure of full-length HPV31 E6 oncoprotein in complex with LXXLL peptide of ubiquitin ligase E6AP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Maltose/maltodextrin-binding periplasmic protein,Protein E6,Ubiquitin-protein ligase E3A | polymer | 551 | 60966.0 | 1 | UniProt (P0AEX9) UniProt (P17386) UniProt (Q05086) Pfam (PF01547) Pfam (PF00518) In PDB | Escherichia coli (strain K12) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,E6AP ubiquitin-protein ligase,HECT-type ubiquitin transferase E3A,Human papillomavirus E6-associated protein,Oncogenic protein-associated protein E6-AP,Renal carcinoma antigen NY-REN-54 |
2 | B | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A: 630 - 1000 (UniProt: P0AEX9)
A: 1001 - 1149 (UniProt: P17386)
A: 1166 - 1180 (UniProt: Q05086)
PDB | External Database | Details |
---|---|---|
Met 630 | Ala 26 | conflict |
Ala 712 | Asp 108 | conflict |
Ala 713 | Lys 109 | conflict |
Ala 869 | Lys 265 | conflict |
Ala 989 | Glu 385 | conflict |
Ala 992 | Lys 388 | conflict |
Ala 993 | Asp 389 | conflict |
Asn 997 | Arg 393 | conflict |
Ala 998 | Ile 394 | conflict |
Ala 999 | Thr 395 | conflict |
Ala 1000 | Lys 396 | conflict |
PDB | External Database | Details |
---|---|---|
Ser 1097 | Cys 97 | conflict |
Ser 1111 | Cys 111 | conflict |
Gly 1150 | - | linker |
Ser 1151 | - | linker |
Ser 1152 | - | linker |
Gly 1153 | - | linker |
Ser 1154 | - | linker |
Gly 1155 | - | linker |
Ser 1156 | - | linker |
Gly 1157 | - | linker |
Ser 1158 | - | linker |
Gly 1159 | - | linker |
Ser 1160 | - | linker |
Gly 1161 | - | linker |
Ser 1162 | - | linker |
Ala 1163 | - | linker |
Ala 1164 | - | linker |
Ala 1165 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 60966.0 | |
Branched | Number of molecules | 1 |
Total formula weight | 342.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 315.0 | |
All* | Total formula weight | 61623.3 |