6SL6

p53 charged core

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cellular tumor antigen p53	polymer	248	27926.6	1	UniProt (P04637) Pfam (PF00870)	Homo sapiens (Human)	Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
2	B, C (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	D (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	E (A)	water	water		18.0	244	Chemie (HOH)

Sequence modifications

A: 89 - 311 (UniProt: P04637)

PDB	External Database	Details
Met 66	-	initiating methionine
Gly 67	-	expression tag
Ser 68	-	expression tag
Ser 69	-	expression tag
His 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
His 73	-	expression tag
His 74	-	expression tag
His 75	-	expression tag
Ser 76	-	expression tag
Ser 77	-	expression tag
Gly 78	-	expression tag
Arg 79	-	expression tag
Glu 80	-	expression tag
Asn 81	-	expression tag
Leu 82	-	expression tag
Tyr 83	-	expression tag
Phe 84	-	expression tag
Gln 85	-	expression tag
Gly 86	-	expression tag
His 87	-	expression tag
Met 88	-	expression tag
Gly 138	Ala 138	engineered mutation
Lys 252	Leu 252	engineered mutation
Arg 256	Thr 256	engineered mutation
Leu 267	Arg 267	engineered mutation
Asp 268	Asn 268	engineered mutation
Gly 312	-	expression tag
Ser 313	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27926.6
Non-Polymers*	Number of molecules	3
	Total formula weight	249.6
All*	Total formula weight	28176.1

*Water molecules are not included.