6SKJ

DeltaC2 C-terminal truncation of HsNMT1 in complex with MyrCoA and GNCFSKPR substrates

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycylpeptide N-tetradecanoyltransferase 1	polymer	400	46224.1	2	UniProt (P30419) Pfam (PF01233) Pfam (PF02799)	Homo sapiens (Human)	Myristoyl-CoA:protein N-myristoyltransferase 1,Type I N-myristoyltransferase,Peptide N-myristoyltransferase 1
2	C, D (C, D)	Apoptosis-inducing factor 3	polymer	8	910.1	2	UniProt (Q96NN9)	Homo sapiens	Apoptosis-inducing factor-like protein
3	E, F, G (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	H (B)	COENZYME A	non-polymer		767.5	1	Chemie (COA)
5	I (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	J, L (C, D)	TETRADECANOYL-COA	non-polymer		977.9	2	Chemie (MYA)
7	K (D)	MYRISTIC ACID	non-polymer		228.4	1	Chemie (MYR)
8	M, N, O, P (A, B, C, D)	water	water		18.0	90	Chemie (HOH)

Sequence modifications

A, B: 99 - 494 (UniProt: P30419)

PDB	External Database	Details
Gly 95	-	expression tag
Gly 96	-	expression tag
Ser 97	-	expression tag
Glu 98	-	expression tag

C, D: 2 - 9 (UniProt: Q96NN9)

PDB	External Database	Details
Asn 3	Gly 3	engineered mutation
Arg 9	Lys 9	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94268.4
Non-Polymers*	Number of molecules	8
	Total formula weight	3252.3
All*	Total formula weight	97520.6

*Water molecules are not included.