6SI5
T. cruzi FPPS in complex with 1-methyl-5-(4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-carbonyl)pyridin-2(1H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyl diphosphate synthase | polymer | 364 | 41359.6 | 1 | UniProt (Q8WS26) Pfam (PF00348) | Trypanosoma cruzi | |
| 2 | B (A) | 5-(6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-ylcarbonyl)-1-methyl-pyridin-2-one | non-polymer | 274.3 | 1 | Chemie (LEQ) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 1 - 362 (UniProt: Q8WS26)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41359.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 466.5 | |
| All* | Total formula weight | 41826.0 |
