6SH7

Crystal structure of the human DEAH-helicase DHX15 in complex with the NKRF G-patch

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15	polymer	689	79063.8	1	UniProt (O43143) Pfam (PF00270) Pfam (PF00271) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) In PDB	Homo sapiens (Human)	ATP-dependent RNA helicase #46,DEAH box protein 15
2	B	NF-kappa-B-repressing factor	polymer	67	7425.5	1	UniProt (O15226) Pfam (PF01585) In PDB	Homo sapiens (Human)	NFkB-repressing factor,Protein ITBA4,Transcription factor NRF
3		water	water		18.0	34	Chemie (HOH)

Sequence modifications

A: 113 - 795 (UniProt: O43143)

PDB	External Database	Details
Gly 107	-	expression tag
Pro 108	-	expression tag
His 109	-	expression tag
Met 110	-	expression tag
Leu 111	-	expression tag
Glu 112	-	expression tag

B: 541 - 603 (UniProt: O15226)

PDB	External Database	Details
Gly 537	-	expression tag
Pro 538	-	expression tag
His 539	-	expression tag
Met 540	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86489.2
All*	Total formula weight	86489.2

*Water molecules are not included.