6SCM
SOS1 in Complex with Inhibitor BI-3406
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Son of sevenless homolog 1 | polymer | 487 | 57103.3 | 1 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) In PDB | Homo sapiens (Human) | SOS-1 |
| 2 | A | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | A | ~{N}-[(1~{R})-1-[3-azanyl-5-(trifluoromethyl)phenyl]ethyl]-7-methoxy-2-methyl-6-[(3~{S})-oxolan-3-yl]oxy-quinazolin-4-amine | non-polymer | 462.5 | 1 | Chemie (L7H) | |||
| 5 | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence modifications
A: 564 - 1049 (UniProt: Q07889)
| PDB | External Database | Details |
|---|---|---|
| Gly 563 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57103.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 911.0 | |
| All* | Total formula weight | 58014.3 |
