Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| A | 0007264 | biological_process | small GTPase-mediated signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue IMD A 1101 |
| Chain | Residue |
| A | TYR884 |
| A | ASP887 |
| A | PHE890 |
| A | IMD1102 |
| A | L7H1108 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue IMD A 1102 |
| Chain | Residue |
| A | TYR884 |
| A | GLU902 |
| A | IMD1101 |
| A | L7H1108 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1103 |
| Chain | Residue |
| A | PHE648 |
| A | GLU649 |
| A | THR720 |
| A | HOH1301 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1104 |
| Chain | Residue |
| A | GLY943 |
| A | ASN944 |
| A | TYR1008 |
| A | ASN1011 |
| A | LYS1012 |
| A | GLU1015 |
| A | HOH1273 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1105 |
| Chain | Residue |
| A | SER633 |
| A | VAL805 |
| A | GLY806 |
| A | GLU941 |
| A | GLU946 |
| A | ARG961 |
| A | LYS1022 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1106 |
| Chain | Residue |
| A | ARG625 |
| A | GLU664 |
| A | ASN691 |
| A | ARG694 |
| A | HIS695 |
| A | HOH1320 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 1107 |
| Chain | Residue |
| A | SER876 |
| A | ASN879 |
| A | TYR912 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue L7H A 1108 |
| Chain | Residue |
| A | GLU590 |
| A | ASN591 |
| A | MET878 |
| A | ASN879 |
| A | TYR884 |
| A | PHE890 |
| A | LYS898 |
| A | GLU902 |
| A | HIS905 |
| A | IMD1101 |
| A | IMD1102 |
Functional Information from PROSITE/UniProt
| site_id | PS00720 |
| Number of Residues | 34 |
| Details | RASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK |
| Chain | Residue | Details |
| A | VAL927-LYS960 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 239 |
| Details | Domain: {"description":"Ras-GEF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00168","evidenceCode":"ECO:0000255"}]} |
