6SBV
X-ray Structure of Human LDH-A with an Allosteric Inhibitor (Compound 7)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | L-lactate dehydrogenase A chain | polymer | 332 | 36660.5 | 8 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (Human) | LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59 |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | ~{N}-[3-[(7-nitrodibenzofuran-2-yl)sulfonylamino]phenyl]-1-oxidanyl-cyclopropane-1-carboxamide | non-polymer | 467.5 | 8 | Chemie (L5K) | |||
| 3 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 2 - 332 (UniProt: P00338)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 293284.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3739.6 | |
| All* | Total formula weight | 297023.8 |
